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SMOX Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR18575N-1 50ul / $395
APR18575N-2 100ul / $495
APR18575N-3 200ul / $595

SMOX Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR18575N

Product Type

Polyclonal Antibodies

Field of Research

Endocrine & Metabolism>Amino acid metabolism

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SMOX Polyclonal Antibody.

Molecular Weight

Calculated MW: 20kDa/43kDa/56kDa/59kDa/61kDa/65kDa Observed MW: Refer to Figures

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human SMOX (NP_787034.1).

Cross Reactivity

Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

Polyamines are ubiquitous polycationic alkylamines which include spermine, spermidine, putrescine, and agmatine. These molecules participate in a broad range of cellular functions which include cell cycle modulation, scavenging reactive oxygen species, and the control of gene expression. These molecules also play important roles in neurotransmission through their regulation of cell-surface receptor activity, involvement in intracellular signalling pathways, and their putative roles as neurotransmitters. This gene encodes an FAD-containing enzyme that catalyzes the oxidation of spermine to spermadine and secondarily produces hydrogen peroxide. Multiple transcript variants encoding different isoenzymes have been identified for this gene, some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates. The characterized isoenzymes have distinctive biochemical characteristics and substrate specificities, suggesting the existence of additional levels of complexity in polyamine catabolism.

Synonyms

SMOX; C20orf16; PAO; PAO-1; PAO1; PAOH; PAOH1; SMO; spermine oxidase

Images

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Specification

Quantity

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