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SPRTN Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR18565N-1 50ul / $395
APR18565N-2 100ul / $495
APR18565N-3 200ul / $595

SPRTN Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR18565N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SPRTN Polyclonal Antibody.

Molecular Weight

Calculated MW: 24kDa/29kDa/55kDa Observed MW: 60kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human SPRTN (NP_001010984.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The protein encoded by this gene may play a role in DNA repair during replication of damaged DNA. This protein recruits valosin containing protein (p97) to stalled DNA replication forks where it may prevent excessive translesional DNA synthesis and limit the number of DNA-damage induced mutations. It may also be involved in replication-related G2/M-checkpoint regulation. Deficiency of a similar protein in mouse causes chromosomal instability and progeroid phenotypes. Mutations in this gene have been associated with Ruijs-Aalfs syndrome (RJALS). Alternatively spliced transcript variants have been identified.

Synonyms

SPRTN; C1orf124; DVC1; PRO4323; spartan; SprT-like N-terminal domain

Images

Western blot analysis of extracts of A-549 cells, using SPRTN antibody.

Specification

Quantity

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