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CXCR3 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR18518N-1 50ul / $395
APR18518N-2 100ul / $495
APR18518N-3 200ul / $595

CXCR3 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR18518N

Product Type

Polyclonal Antibodies

Field of Research

Neuroscience>Calcium Signaling

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CXCR3 Polyclonal Antibody.

Molecular Weight

Calculated MW: 28kDa/40kDa/45kDa Observed MW: 41kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CXCR3 (NP_001495.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).

Synonyms

CXCR3; CD182; CD183; CKR-L2; CMKAR3; GPR9; IP10-R; Mig-R; MigR; C-X-C chemokine receptor type 3

Images

Western blot analysis of extracts of various cell lines, using CXCR3 Antibody.

Specification

Quantity

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