> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Histone H2AX Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR18492N |
Product Type |
Polyclonal Antibodies | Field of Research |
Epigenetics & Nuclear Signaling>DNA Damage & Repair |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Histone H2AX Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
15kDa
Observed MW:
15kDa
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant protein of human Histone H2AX
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Cross Reactivity |
Human,Mouse,Rat
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IHC,IF
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Dilution |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
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Product Description |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
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Synonyms |
H2AFX; H2A.X; H2A/X; H2AX; histone H2AX
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Images |
Western blot analysis of extracts of various cell lines, using Histone H2AX antibody.
Immunohistochemistry of paraffin-embedded rat testis using Histone H2AX antibody.
Immunohistochemistry of paraffin-embedded mouse testis using Histone H2AX antibody. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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