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TNF-α Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR18490N-1 50ul / $395
APR18490N-2 100ul / $495
APR18490N-3 200ul / $595

TNF-α Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR18490N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TNF-α Polyclonal Antibody.

Molecular Weight

Calculated MW: 25kDa Observed MW: 21kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human TNF

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:1000 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100

Product Description

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

Synonyms

TNF; DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F; tumor necrosis factor

Images

Western blot analysis of extracts of various cell lines, using TNF-α antibody.

Immunohistochemistry of paraffin-embedded human stomach using TNF-α antibody.

Immunofluorescence analysis of RAW264.7 cells using TNF-α antibody.

Specification

Quantity

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