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BMP4 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR18410N-1 50ul / $395
APR18410N-2 100ul / $495
APR18410N-3 200ul / $595

BMP4 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR18410N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Angiogenesis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BMP4 Polyclonal Antibody.

Molecular Weight

Calculated MW: 46kDa Observed MW: _

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human BMP4 (NP_570912.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers.

Synonyms

BMP4; BMP2B; BMP2B1; MCOPS6; OFC11; ZYME; bone morphogenetic protein 4

Images

Immunohistochemistry of paraffin-embedded human prostate cancer using BMP4 antibody.

Immunohistochemistry of paraffin-embedded mouse lung using BMP4 antibody.

Specification

Quantity

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