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Parkin Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR18363N-1 50ul / $395
APR18363N-2 100ul / $495
APR18363N-3 200ul / $595

Parkin Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR18363N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Autophagy

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Parkin Polyclonal Antibody.

Molecular Weight

Calculated MW: 23kDa/30-51kDa Observed MW: 52kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human Parkin

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.

Synonyms

PRKN; AR-JP; LPRS2; PARK2; PDJ; E3 ubiquitin-protein ligase parkin

Images

Western blot analysis of extracts of various cell lines, using Parkin antibody.

Immunofluorescence analysis of A549 cells using Parkin antibody.

Specification

Quantity

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