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DAZL Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR18349N-1 50ul / $395
APR18349N-2 100ul / $495
APR18349N-3 200ul / $595

DAZL Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR18349N

Product Type

Polyclonal Antibodies

Field of Research

Stem Cells>Germline Stem Cells

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DAZL Polyclonal Antibody.

Molecular Weight

Calculated MW: 33kDa/35kDa Observed MW: 33kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human DAZL (NP_001342.2).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms

DAZL; DAZH; DAZL1; DAZLA; SPGYLA; deleted in azoospermia-like

Images

Western blot analysis of extracts of various cell lines, using DAZL antibody.

Immunofluorescence analysis of HeLa cells using DAZL antibody.

Specification

Quantity

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