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UBE2K Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR18301N-1 50ul / $395
APR18301N-2 100ul / $495
APR18301N-3 200ul / $595

UBE2K Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR18301N

Product Type

Polyclonal Antibodies

Field of Research

Neuroscience>Neurodegenerative Diseases

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality UBE2K Polyclonal Antibody.

Molecular Weight

Calculated MW: 16kDa/17kDa/22kDa Observed MW: 22kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human UBE2K (NP_005330.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.

Synonyms

UBE2K; E2-25K; HIP2; HYPG; LIG; UBC1; ubiquitin-conjugating enzyme E2 K

Images

Western blot analysis of extracts of various cell lines, using UBE2K antibody.

Specification

Quantity

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