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UBE2D2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR18286N-1 50ul / $395
APR18286N-2 100ul / $495
APR18286N-3 200ul / $595

UBE2D2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR18286N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Ubiquitin

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality UBE2D2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 13kDa/16kDa Observed MW: 17kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human UBE2D2 (NP_003330.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene.

Synonyms

UBE2D2; E2(17)KB2; PUBC1; UBC4; UBC4/5; UBCH4; UBCH5B; ubiquitin-conjugating enzyme E2 D2

Images

Western blot analysis of extracts of various cell lines, using UBE2D2 antibody.

Specification

Quantity

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