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MTMR3 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR18280N-1 50ul / $395
APR18280N-2 100ul / $495
APR18280N-3 200ul / $595

MTMR3 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR18280N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Autophagy

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MTMR3 Polyclonal Antibody.

Molecular Weight

Calculated MW: 129kDa/130kDa/133kDa Observed MW: 134kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human MTMR3 (NP_066576.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:100

Product Description

This gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol(3)-phosphate and phosphatidylinositol(3,5)-biphosphate in vitro. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

MTMR3; FYVE-DSP1; ZFYVE10; myotubularin-related protein 3

Images

Western blot analysis of extracts of various cell lines, using MTMR3 antibody.

Specification

Quantity

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