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SAV1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28819N-1 50ul / $395
APR28819N-2 100ul / $495
APR28819N-3 200ul / $595

SAV1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28819N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Hippo Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SAV1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 44kDa Observed MW: 45kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human SAV1 (NP_068590.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:1000 - 1:4000

Product Description

WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.

Synonyms

SAV1; SAV; WW45; WWP4; protein salvador homolog 1

Images

Western blot analysis of extracts of various cell lines, using SAV1 antibody.

Specification

Quantity

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