> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SOCS6 Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR28796N |
Product Type |
Polyclonal Antibodies | Field of Research |
Immunology & Inflammation>Jak-Stat-IL-6 Receptor Signaling Pathway |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SOCS6 Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
59kDa
Observed MW:
70kDa
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant fusion protein of human SOCS6 (NP_004223.2).
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Cross Reactivity |
Human,Mouse
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IHC
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Dilution |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
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Product Description |
The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.
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Synonyms |
SOCS6; CIS-4; CIS4; HSPC060; SOCS-4; SOCS-6; SOCS4; SSI4; STAI4; STATI4; suppressor of cytokine signaling 6
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Images |
Western blot analysis of extracts of various cell lines, using SOCS6 antibody.
Immunohistochemistry of paraffin-embedded human mammary cancer using SOCS6 antibody.
Immunohistochemistry of paraffin-embedded human liver cancer using SOCS6 antibody. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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