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SOCS6 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28796N-1 50ul / $395
APR28796N-2 100ul / $495
APR28796N-3 200ul / $595

SOCS6 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28796N

Product Type

Polyclonal Antibodies

Field of Research

Immunology & Inflammation>Jak-Stat-IL-6 Receptor Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SOCS6 Polyclonal Antibody.

Molecular Weight

Calculated MW: 59kDa Observed MW: 70kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human SOCS6 (NP_004223.2).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.

Synonyms

SOCS6; CIS-4; CIS4; HSPC060; SOCS-4; SOCS-6; SOCS4; SSI4; STAI4; STATI4; suppressor of cytokine signaling 6

Images

Western blot analysis of extracts of various cell lines, using SOCS6 antibody.

Immunohistochemistry of paraffin-embedded human mammary cancer using SOCS6 antibody.

Immunohistochemistry of paraffin-embedded human liver cancer using SOCS6 antibody.

Specification

Quantity

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