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RGS10 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28787N-1 50ul / $395
APR28787N-2 100ul / $495
APR28787N-3 200ul / $595

RGS10 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28787N

Product Type

Polyclonal Antibodies

Field of Research

Signal Transduction>G protein signaling

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RGS10 Polyclonal Antibody.

Molecular Weight

Calculated MW: 19kDa/20kDa/21kDa Observed MW: 20kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human RGS10 (NP_001005339.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms

RGS10; regulator of G-protein signaling 10

Images

Western blot analysis of extracts of various cell lines, using RGS10 antibody.

Specification

Quantity

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