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NODAL Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28764N-1 50ul / $395
APR28764N-2 100ul / $495
APR28764N-3 200ul / $595

NODAL Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28764N

Product Type

Polyclonal Antibodies

Field of Research

Immunology & Inflammation>Cytokines

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NODAL Polyclonal Antibody.

Molecular Weight

Calculated MW: 39kDa Observed MW: 44kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human NODAL (NP_060525.3).

Cross Reactivity

Human,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. This protein is required for maintenance of human embryonic stem cell pluripotency and may play a role in human placental development. Mutations in this gene are associated with heterotaxy, a condition characterized by random orientation of visceral organs with respect to the left-right axis.

Synonyms

NODAL; HTX5; nodal homolog

Images

Western blot analysis of extracts of various cell lines, using NODAL antibody.

Specification

Quantity

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