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CAMKK2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28762N-1 50ul / $395
APR28762N-2 100ul / $495
APR28762N-3 200ul / $595

CAMKK2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28762N

Product Type

Polyclonal Antibodies

Field of Research

Endocrine & Metabolism>AMPK Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CAMKK2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 54kDa/58kDa/59kDa/61kDa/64kDa Observed MW: 65kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CAMKK2 (NP_757380.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases.

Synonyms

CAMKK2; CAMKK; CAMKKB; calcium/calmodulin-dependent protein kinase kinase 2

Images

Western blot analysis of extracts of H460 cells, using CAMKK2 antibody.

Specification

Quantity

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