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ABCB4 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28701N-1 50ul / $395
APR28701N-2 100ul / $495
APR28701N-3 200ul / $595

ABCB4 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28701N

Product Type

Polyclonal Antibodies

Field of Research

Endocrine & Metabolism>Lipid Metabolism

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ABCB4 Polyclonal Antibody.

Molecular Weight

Calculated MW: 135kDa/140kDa/141kDa Observed MW: 144kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human ABCB4 (NP_061337.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function.

Synonyms

ABCB4; ABC21; GBD1; ICP3; MDR2; MDR2/3; MDR3; PFIC-3; PGY3; phosphatidylcholine translocator ABCB4

Images

Western blot analysis of extracts of mouse brain, using ABCB4 antibody.

Specification

Quantity

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