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MYO5A Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28696N-1 50ul / $395
APR28696N-2 100ul / $495
APR28696N-3 200ul / $595

MYO5A Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28696N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cytoskeleton

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MYO5A Polyclonal Antibody.

Molecular Weight

Calculated MW: 212kDa/215kDa/218kDa Observed MW: 240kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human MYO5A (NP_000250.3).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100

Product Description

This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined.

Synonyms

MYO5A; GS1; MYH12; MYO5; MYR12; myosin VA

Images

Western blot analysis of extracts of various cell lines, using MYO5A antibody.

Immunohistochemistry of paraffin-embedded rat kidney using MYO5A antibody.

Immunohistochemistry of paraffin-embedded human liver cancer using MYO5A antibody.

Specification

Quantity

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