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RFXAP Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28590N-1 50ul / $395
APR28590N-2 100ul / $495
APR28590N-3 200ul / $595

RFXAP Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28590N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RFXAP Polyclonal Antibody.

Molecular Weight

Calculated MW: 28kDa Observed MW: Refer to figures

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human RFXAP (NP_000529.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene.

Synonyms

RFXAP; regulatory factor X-associated protein

Images

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Specification

Quantity

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