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WNT3 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28576N-1 50ul / $395
APR28576N-2 100ul / $495
APR28576N-3 200ul / $595

WNT3 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28576N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>ESC Pluripotency and Differentiation

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality WNT3 Polyclonal Antibody.

Molecular Weight

Calculated MW: 39kDa Observed MW: 45kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human WNT3 (NP_110380.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:200 - 1:2000

Product Description

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.

Synonyms

WNT3; INT4; TETAMS; Wnt family member 3

Images

Western blot analysis of extracts of various cell lines, using WNT3 antibody.

Specification

Quantity

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