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SEC31A Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28571N-1 50ul / $395
APR28571N-2 100ul / $495
APR28571N-3 200ul / $595

SEC31A Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28571N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SEC31A Polyclonal Antibody.

Molecular Weight

Calculated MW: 56kDa/105-134kDa Observed MW: 165kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human SEC31A (NP_055748.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:1000 - 1:2000 IF 1:50 - 1:200

Product Description

The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms

SEC31A; ABP125; ABP130; HSPC275; HSPC334; SEC31L1; protein transport protein Sec31A

Images

Western blot analysis of extracts of various cell lines, using SEC31A antibody.

Specification

Quantity

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