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CACNB4 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28568N-1 50ul / $395
APR28568N-2 100ul / $495
APR28568N-3 200ul / $595

CACNB4 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28568N

Product Type

Polyclonal Antibodies

Field of Research

Neuroscience>Calcium Signaling

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CACNB4 Polyclonal Antibody.

Molecular Weight

Calculated MW: 51kDa/54kDa/56kDa/58kDa Observed MW: 58kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CACNB4 (NP_000717.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:1000 - 1:2000

Product Description

This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME). Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

CACNB4; CAB4; CACNLB4; EA5; EIG9; EJM; EJM4; EJM6; calcium voltage-gated channel auxiliary subunit beta 4

Images

Western blot analysis of extracts of various cell lines, using CACNB4 antibody.

Specification

Quantity

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