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SNX15 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28525N-1 50ul / $395
APR28525N-2 100ul / $495
APR28525N-3 200ul / $595

SNX15 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28525N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SNX15 Polyclonal Antibody.

Molecular Weight

Calculated MW: 29kDa/38kDa Observed MW: 50kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human SNX15 (NP_037438.2).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene.

Synonyms

SNX15; HSAF001435; sorting nexin-15

Images

Western blot analysis of extracts of various cell lines, using SNX15 antibody.

Specification

Quantity

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