> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > RNASEH1 Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR28514N |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RNASEH1 Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
32kDa
Observed MW:
37kDa
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant fusion protein of human RNASEH1 (NP_002927.2).
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Cross Reactivity |
Human,Mouse,Rat
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IHC
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Dilution |
WB 1:500 - 1:2000
IHC 1:100 - 1:200
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Product Description |
This gene encodes an endonuclease that specifically degrades the RNA of RNA-DNA hybrids and is necessary for DNA replication and repair. This enzyme is present in both mitochondria and nuclei, which are resulted from translation of a single mRNA with two in-frame initiation start codons. The use of the first start codon produces the mitochondrial isoform and the use of the second start codon produces the nuclear isoform. The production of the mitochondrial isoform is modulated by an upstream open reading frame (uORF) which overlaps the first initiation start codon in human. An alternately spliced transcript variant has been found which encodes a shorter isoform. This gene has three pseudogenes; two of them are at different locations of chromosome 17 and one of them is on chromosome 1q32.2.
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Synonyms |
RNASEH1; H1RNA; PEOB2; RNH1; ribonuclease H1
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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