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CNOT7 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28469N-1 50ul / $395
APR28469N-2 100ul / $495
APR28469N-3 200ul / $595

CNOT7 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28469N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CNOT7 Polyclonal Antibody.

Molecular Weight

Calculated MW: 28kDa/32kDa Observed MW: 33kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CNOT7 (NP_037486.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:200 - 1:2000

Product Description

The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.

Synonyms

CNOT7; CAF-1; CAF1; Caf1a; hCAF-1; CCR4-NOT transcription complex subunit 7

Images

Western blot analysis of extracts of various cell lines, using CNOT7 antibody.

Specification

Quantity

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