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PBXIP1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28437N-1 50ul / $395
APR28437N-2 100ul / $495
APR28437N-3 200ul / $595

PBXIP1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28437N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>Nuclear Receptor Signaling

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PBXIP1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 72kDa/77kDa/80kDa Observed MW: 110kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PBXIP1 (NP_065385.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:1000 - 1:2000 IHC 1:50 - 1:200

Product Description

The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer, brain tumors, and lung cancer. Several transcript variants encoding different isoforms have been found for this gene. More variants exist, but their full-length natures have yet to be determined.

Synonyms

PBXIP1; HPIP; PBX homeobox interacting protein 1

Images

Western blot analysis of extracts of various cell lines, using PBXIP1 antibody.

Specification

Quantity

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