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CENPJ Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28416N-1 50ul / $395
APR28416N-2 100ul / $495
APR28416N-3 200ul / $595

CENPJ Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28416N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Cycle

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CENPJ Polyclonal Antibody.

Molecular Weight

Calculated MW: 124kDa/153kDa Observed MW: 153kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CENPJ (NP_060921.3).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation. Alternatively spliced transcript variants have been found for this gene.

Synonyms

CENPJ; BM032; CENP-J; CPAP; LAP; LIP1; MCPH6; SASS4; SCKL4; Sas-4; centromere protein J

Images

Western blot analysis of extracts of Raji cells, using CENPJ Antibody.

Specification

Quantity

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