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DDX50 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28389N-1 50ul / $395
APR28389N-2 100ul / $495
APR28389N-3 200ul / $595

DDX50 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28389N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>RNA Binding

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DDX50 Polyclonal Antibody.

Molecular Weight

Calculated MW: 82kDa Observed MW: 105kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human DDX50 (NP_076950.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:200 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box enzyme that may be involved in ribosomal RNA synthesis or processing. This gene and DDX21, also called RH-II/GuA, have similar genomic structures and are in tandem orientation on chromosome 10, suggesting that the two genes arose by gene duplication in evolution. This gene has pseudogenes on chromosomes 2, 3 and 4. Alternative splicing of this gene generates multiple transcript variants, but the full length nature of all the other variants but one has not been defined.

Synonyms

DDX50; GU2; GUB; RH-II/GuB; mcdrh; DExD-box helicase 50

Images

Western blot analysis of extracts of various cell lines, using DDX50 antibody.

Immunohistochemistry of paraffin-embedded mouse testis using DDX50 antibody.

Immunohistochemistry of paraffin-embedded mouse brain using DDX50 antibody.

Specification

Quantity

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