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HNRPH3 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28329N-1 50ul / $395
APR28329N-2 100ul / $495
APR28329N-3 200ul / $595

HNRPH3 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28329N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>RNA Binding

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HNRPH3 Polyclonal Antibody.

Molecular Weight

Calculated MW: 15kDa/16kDa/22kDa/31kDa/35kDa/36kDa Observed MW: _

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human HNRPH3 (NP_067676.2).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

IF

Dilution

IF 1:50 - 1:200

Product Description

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is localized in nuclear bodies of the nucleus. This protein is involved in the splicing process and it also participates in early heat shock-induced splicing arrest by transiently leaving the hnRNP complexes. Several alternatively spliced transcript variants have been noted for this gene, however, not all are fully characterized.

Synonyms

HNRNPH3; 2H9; HNRPH3; heterogeneous nuclear ribonucleoprotein H3

Images

Immunofluorescence analysis of 293T cells using HNRNPH3 antibody.

Specification

Quantity

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