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CKAP5 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28315N-1 50ul / $395
APR28315N-2 100ul / $495
APR28315N-3 200ul / $595

CKAP5 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28315N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Cycle

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CKAP5 Polyclonal Antibody.

Molecular Weight

Calculated MW: 218kDa/225kDa/226kDa Observed MW: 250kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CKAP5 (NP_001008938.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation; it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified.

Synonyms

CKAP5; CHTOG; MSPS; TOG; TOGp; ch-TOG; cytoskeleton-associated protein 5

Images

Western blot analysis of extracts of various cell lines, using CKAP5 antibody.

Specification

Quantity

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