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EHMT1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28299N-1 50ul / $395
APR28299N-2 100ul / $495
APR28299N-3 200ul / $595

EHMT1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28299N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>Epigenetic writers and erasers of core Histones

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality EHMT1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 7kDa/86kDa/128kDa/141kDa Observed MW: 141kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human EHMT1 (NP_079033.4).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The protein encoded by this gene is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. The encoded protein methylates the Lys-9 position of histone H3, which tags it for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants.

Synonyms

EHMT1; EUHMTASE1; Eu-HMTase1; FP13812; GLP; GLP1; KMT1D; bA188C12.1; histone-lysine N-methyltransferase EHMT1

Images

Western blot analysis of extracts of various cell lines, using EHMT1 antibody.

Specification

Quantity

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