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LPIN1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28272N-1 50ul / $395
APR28272N-2 100ul / $495
APR28272N-3 200ul / $595

LPIN1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28272N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Cardiovascular diseases

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LPIN1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 50kDa/98kDa/99-107kDa Observed MW: 113kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human LPIN1 (NP_663731.1).

Cross Reactivity

Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined.

Synonyms

LPIN1; PAP1; lipin 1

Images

Western blot analysis of extracts of rat skeletal muscle, using LPIN1 antibody.

Specification

Quantity

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