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MAP3K12 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28251N-1 50ul / $395
APR28251N-2 100ul / $495
APR28251N-3 200ul / $595

MAP3K12 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28251N

Product Type

Polyclonal Antibodies

Field of Research

Immunology & Inflammation>B Cell Receptor Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MAP3K12 Polyclonal Antibody.

Molecular Weight

Calculated MW: 93kDa/96kDa Observed MW: 120kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human MAP3K12 (NP_001180440.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.

Synonyms

MAP3K12; DLK; MEKK12; MUK; ZPK; ZPKP1; mitogen-activated protein kinase kinase kinase 12

Images

Western blot analysis of extracts of various cell lines, using MAP3K12 antibody.

Specification

Quantity

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