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ATP7A Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28186N-1 50ul / $395
APR28186N-2 100ul / $495
APR28186N-3 200ul / $595

ATP7A Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28186N

Product Type

Polyclonal Antibodies

Field of Research

Neuroscience>Neurodegenerative Diseases

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ATP7A Polyclonal Antibody.

Molecular Weight

Calculated MW: 11kDa/54kDa/154kDa/163kDa/165kDa/172kDa Observed MW: 163kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human ATP7A (NP_000043.4).

Cross Reactivity

Human,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100

Product Description

This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed.

Synonyms

ATP7A; DSMAX; MK; MNK; SMAX3; copper-transporting ATPase 1

Images

Western blot analysis of extracts of 293T cells, using ATP7A antibody.

Immunohistochemistry of paraffin-embedded rat kidney using ATP7A antibody.

Immunohistochemistry of paraffin-embedded human liver damage using ATP7A antibody.

Specification

Quantity

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