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CFTR Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28174N-1 50ul / $395
APR28174N-2 100ul / $495
APR28174N-3 200ul / $595

CFTR Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28174N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CFTR Polyclonal Antibody.

Molecular Weight

Calculated MW: 69kDa/161kDa/168kDa Observed MW: 186kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CFTR (NP_000483.3).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily that is involved in multi-drug resistance. The encoded protein functions as a chloride channel and controls the regulation of other transport pathways. Mutations in this gene are associated with the autosomal recessive disorders cystic fibrosis and congenital bilateral aplasia of the vas deferens. Alternatively spliced transcript variants have been described, many of which result from mutations in this gene.

Synonyms

CFTR; ABC35; ABCC7; CF; CFTR/MRP; MRP7; TNR-CFTR; dJ760C5.1; cystic fibrosis transmembrane conductance regulator

Images

Western blot analysis of extracts of HL-60 cells, using CFTR antibody.

Specification

Quantity

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