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NUP214 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28147N-1 50ul / $395
APR28147N-2 100ul / $495
APR28147N-3 200ul / $595

NUP214 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28147N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>Nuclear Receptor Signaling

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NUP214 Polyclonal Antibody.

Molecular Weight

Calculated MW: 212kDa/213kDa/215kDa Observed MW: 251kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human NUP214 (NP_005076.3).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:100

Product Description

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene is a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is localized to the cytoplasmic face of the nuclear pore complex where it is required for proper cell cycle progression and nucleocytoplasmic transport. The 3' portion of this gene forms a fusion gene with the DEK gene on chromosome 6 in a t(6,9) translocation associated with acute myeloid leukemia and myelodysplastic syndrome. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

Synonyms

NUP214; CAIN; CAN; nucleoporin 214

Images

Western blot analysis of extracts of various cell lines, using NUP214 antibody.

Immunofluorescence analysis of L929 cells using NUP214 Polyclonal Antibody.

Specification

Quantity

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