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CAD Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28134N-1 50ul / $395
APR28134N-2 100ul / $495
APR28134N-3 200ul / $595

CAD Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28134N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CAD Polyclonal Antibody.

Molecular Weight

Calculated MW: 242kDa Observed MW: 243kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CAD (NP_004332.2).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:200

Product Description

The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms

CAD; CDG1Z; EIEE50; GATD4; CAD protein

Images

Western blot analysis of extracts of various cell lines, using CAD antibody.

Immunohistochemistry of paraffin-embedded human liver using CAD antibody.

Immunohistochemistry of paraffin-embedded human stomach using CAD antibody.

Specification

Quantity

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