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OPRK1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28102N-1 50ul / $395
APR28102N-2 100ul / $495
APR28102N-3 200ul / $595

OPRK1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28102N

Product Type

Polyclonal Antibodies

Field of Research

Signal Transduction>G protein signaling

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality OPRK1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 33kDa/42kDa Observed MW: 43kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human OPRK1 (NP_000903.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.

Synonyms

OPRK1; K-OR-1; KOR; KOR-1; OPRK; opioid receptor kappa 1

Images

Western blot analysis of extracts of various cell lines, using OPRK1 antibody.

Specification

Quantity

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