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NOTCH4 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28099N-1 50ul / $395
APR28099N-2 100ul / $495
APR28099N-3 200ul / $595

NOTCH4 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28099N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Angiogenesis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NOTCH4 Polyclonal Antibody.

Molecular Weight

Calculated MW: 39kDa/61kDa/209kDa Observed MW: 88kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human NOTCH4 (NP_004548.3).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor may play a role in vascular, renal and hepatic development. Mutations in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Synonyms

NOTCH4; INT3; notch 4

Images

Western blot analysis of extracts of Mouse kidney, using NOTCH4 antibody.

Specification

Quantity

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