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RSPO1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28091N-1 50ul / $395
APR28091N-2 100ul / $495
APR28091N-3 200ul / $595

RSPO1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28091N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RSPO1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 21kDa/25kDa/28kDa Observed MW: 29kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human RSPO1 (NP_001033722.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100

Product Description

This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants.

Synonyms

RSPO1; CRISTIN3; RSPO; R-spondin-1

Images

Western blot analysis of extracts of various cell lines, using RSPO1 antibody.

Immunohistochemistry of paraffin-embedded rat lung using RSPO1 antibody.

Immunohistochemistry of paraffin-embedded mouse lung using RSPO1 antibody.

Specification

Quantity

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