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EXOC2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28058N-1 50ul / $395
APR28058N-2 100ul / $495
APR28058N-3 200ul / $595

EXOC2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28058N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality EXOC2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 104kDa Observed MW: 108kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human EXOC2 (NP_060773.3).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants.

Synonyms

EXOC2; SEC5; SEC5L1; Sec5p; exocyst complex component 2

Images

Western blot analysis of extracts of various cell lines, using EXOC2 antibody.

Immunofluorescence analysis of U2OS cells using EXOC2 antibody.

Specification

Quantity

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