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ARFGAP3 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28037N-1 50ul / $395
APR28037N-2 100ul / $495
APR28037N-3 200ul / $595

ARFGAP3 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28037N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ARFGAP3 Polyclonal Antibody.

Molecular Weight

Calculated MW: 51kDa/56kDa Observed MW: 57kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human ARFGAP3 (NP_055385.3).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100

Product Description

The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene.

Synonyms

ARFGAP3; ARFGAP1; ADP-ribosylation factor GTPase-activating protein 3

Images

Western blot analysis of extracts of various cell lines, using ARFGAP3 antibody.

Immunohistochemistry of paraffin-embedded mouse stomach using ARFGAP3 antibody.

Immunohistochemistry of paraffin-embedded human liver cancer using ARFGAP3 antibody.

Specification

Quantity

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