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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > [KO Validated] POR Polyclonal Antibody

[KO Validated] POR Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27990N-1 50ul / $395
APR27990N-2 100ul / $495
APR27990N-3 200ul / $595

[KO Validated] POR Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27990N

Product Type

Polyclonal Antibodies

Field of Research

Endocrine & Metabolism>Drug metabolism

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality [KO Validated] POR Polyclonal Antibody.

Molecular Weight

Calculated MW: 76kDa Observed MW: 77kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human POR (NP_000932.3).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:200

Product Description

This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.

Synonyms

POR; CPR; CYPOR; P450R; cytochrome p450 oxidoreductase

Images

Western blot analysis of extracts of various cell lines, using POR antibody.

Western blot analysis of extracts from normal (control) and POR knockout (KO) HeLa cells, using POR antibody.

Immunohistochemistry of paraffin-embedded human esophagus using POR antibody.

Specification

Quantity

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