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CKMT2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27948N-1 50ul / $395
APR27948N-2 100ul / $495
APR27948N-3 200ul / $595

CKMT2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27948N

Product Type

Polyclonal Antibodies

Field of Research

Endocrine & Metabolism>Mitochondrial metabolism

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CKMT2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 47kDa Observed MW: 40kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CKMT2 (NP_001816.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:20 - 1:200

Product Description

Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.

Synonyms

CKMT2; SMTCK; creatine kinase, mitochondrial 2

Images

Western blot analysis of extracts of various cell lines, using CKMT2 antibody.

Immunohistochemistry of paraffin-embedded rat heart using CKMT2 antibody.

Immunohistochemistry of paraffin-embedded human esophagus using CKMT2 antibody.

Specification

Quantity

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