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ANAPC2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27934N-1 50ul / $395
APR27934N-2 100ul / $495
APR27934N-3 200ul / $595

ANAPC2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27934N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Cycle

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ANAPC2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 93kDa Observed MW: 102kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human ANAPC2 (NP_037498.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation.

Synonyms

ANAPC2; APC2; anaphase-promoting complex subunit 2

Images

Western blot analysis of extracts of various cell lines, using ANAPC2 antibody.

Specification

Quantity

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