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HMGCL Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27920N-1 50ul / $395
APR27920N-2 100ul / $495
APR27920N-3 200ul / $595

HMGCL Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27920N

Product Type

Polyclonal Antibodies

Field of Research

Endocrine & Metabolism>Amino acid metabolism

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HMGCL Polyclonal Antibody.

Molecular Weight

Calculated MW: 20kDa/26kDa/34kDa Observed MW: 30kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human HMGCL (NP_000182.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Synonyms

HMGCL; HL; 3-hydroxymethyl-3-methylglutaryl-CoA lyase

Images

Western blot analysis of extracts of various cell lines, using HMGCL antibody.

Immunohistochemistry of paraffin-embedded rat kidney using HMGCL antibody.

Immunohistochemistry of paraffin-embedded human colon carcinoma using HMGCL antibody.

Specification

Quantity

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