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RRM2B Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27902N-1 50ul / $395
APR27902N-2 100ul / $495
APR27902N-3 200ul / $595

RRM2B Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27902N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>DNA Damage & Repair

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RRM2B Polyclonal Antibody.

Molecular Weight

Calculated MW: 4kDa/7kDa/15kDa/34kDa/40kDa/48kDa Observed MW: Refer to figures

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human RRM2B (NP_056528.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:100

Product Description

This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.

Synonyms

RRM2B; MTDPS8A; MTDPS8B; P53R2; ribonucleoside-diphosphate reductase subunit M2 B

Images

Immunofluorescence analysis of A549 cells using RRM2B antibody.

Specification

Quantity

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