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ARTN Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27842N-1 50ul / $395
APR27842N-2 100ul / $495
APR27842N-3 200ul / $595

ARTN Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27842N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Growth factors

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ARTN Polyclonal Antibody.

Molecular Weight

Calculated MW: 22kDa/23kDa/24kDa Observed MW: 28kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human ARTN

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein signals through the RET receptor and GFR alpha 3 coreceptor, and supports the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. This protein has also been shown to promote tumor growth, metastasis, and drug resistance in mammary carcinoma.

Synonyms

ARTN; ART; ENOVIN; EVN; NBN; artemin

Images

Western blot analysis of extracts of 22Rv1 cells, using ARTN antibody.

Specification

Quantity

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