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WHSC1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27832N-1 50ul / $395
APR27832N-2 100ul / $495
APR27832N-3 200ul / $595

WHSC1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27832N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>Epigenetic writers and erasers of core Histones

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality WHSC1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 30kDa/53kDa/66kDa/69kDa/71kDa/80kDa/152kDa Observed MW: 80kDa, 152kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human WHSC1 (NP_579877.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.

Synonyms

NSD2; KMT3F; KMT3G; MMSET; REIIBP; TRX5; WHS; WHSC1; histone-lysine N-methyltransferase NSD2

Images

Western blot analysis of extracts of various cell lines, using WHSC1 antibody.

Immunohistochemistry of paraffin-embedded mouse lung using WHSC1 antibody.

Immunohistochemistry of paraffin-embedded mouse kidney using WHSC1 antibody.

Specification

Quantity

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