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TAF11 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27830N-1 50ul / $395
APR27830N-2 100ul / $495
APR27830N-3 200ul / $595

TAF11 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27830N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TAF11 Polyclonal Antibody.

Molecular Weight

Calculated MW: 17kDa/23kDa Observed MW: 23kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human TAF11 (NP_005634.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms

TAF11; MGC:15243; PRO2134; TAF2I; TAFII28; TATA-box binding protein associated factor 11

Images

Western blot analysis of extracts of various cell lines, using TAF11 antibody.

Immunofluorescence analysis of U2OS cells using TAF11 antibody.

Specification

Quantity

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